姓名： 刘臣

管理类别： 教学科研系列

所在单位： 四川农业大学园艺学院 茶学系

学位： Doctor of Philosophy（Wageningen University, 2022）

导师类别： 硕士研究生导师

资格与荣誉： European Registered Toxicologist (ERT, 2023)

主要研究领域

· 茶叶功能成分与人体健康

· 功能食品的开发与评价

· 茶叶加工与品质化学

· 基于生理动力学的 PBPK 建模

· 食源性化合物的毒理与风险评估

学习与工作经历

· 2011.09–2015.06 西北农林科技大学 森林资源保护与游憩专业，本科

· 2015.09–2018.06 中国农业科学院植物保护研究所 农业昆虫与害虫防治专业，硕士

· 2018.11–2022.06 Wageningen University, Department of Toxicology，博士（PhD in Toxicology）

· 2022.08–至今 四川农业大学园艺学院茶学系任教，讲师（特聘副教授）

主持科研项目

· 2025–2027 年：主持，四川省微生物省重点实验室开放课题

· 2025–2027 年：主持，拉萨市科技局重点研发项目

· 2024–2026 年：主持，四川农业大学自主探索项目

· 2024–2025 年：主持，四川省科技厅国际合作项目

· 2023–2025 年：主持，茶树生物学与资源利用国家重点实验室开放课题

· 2022–2027 年：主持，四川农业大学“学术骨干计划”科研启动基金

代表性科研成果（第一 / 通讯 / 共同第一作者）

1. Chen Liu* et al. (2020). Interindividual differences in human in vitro intestinal microbial conversion of green tea (-)-epigallocatechin-3-O-gallate and consequences for activation of Nrf2-mediated gene expression. Molecular Nutrition and Food Research, IF：5.9. 中科院一区

2. Chen Liu* et al. (2020). Interindividual differences in human intestinal microbial conversion of (-)-epicatechin to bioactive phenolic compounds. Journal of Agricultural and Food Chemistry, IF：5.3. 中科院一区

3. Chen Liu* et al. (2022). Use of physiologically based kinetic modeling-based reverse dosimetry to predict in vivo Nrf2 activation by EGCG and its colonic metabolites in humans. Journal of Agricultural and Food Chemistry, IF：5.9. 中科院一区

4. Chen Liu* et al. (2022). The gut microbial metabolite pyrogallol is a more potent inducer of Nrf2-associated gene expression than its parent compound green tea (-)-epigallocatechin gallate. Nutrients, IF：6.7. 中科院二区TOP

5. Chen Liu* et al. (2022). Intra- and inter-individual differences in the human intestinal microbial conversion of (-)-epicatechin and bioactivity of its major colonic metabolite 5-(3′,4′-dihydroxy-phenyl)-γ-valerolactone in regulating Nrf2-mediated gene expression. Frontiers in Nutrition, IF：6.6. 中科院二区

6. Xue Yao¹, Chen Liu¹ (共一) et al. (2022). ABCC2 is a functional receptor of Bacillus thuringiensis Cry1Ca in Spodoptera litura. International Journal of Biological Macromolecules, IF：8.2. 中科院一区

7. Chen Liu* et al. (2023). Gut microbiota-mediated metabolism of green tea catechins and the biological consequences: An updated review. Critical Reviews in Food Science and Nutrition, 64(20): 7067–7084, IF：10.2. 中科院一区

8. Chen Liu* et al. (2023). New approach methodologies (NAMs) to study microbiome–host interactions. Current Opinion in Toxicology, IF：6.1. 中科院三区

9. Chen Liu et al. (2025). Theabrownin: The “rich hue” of Chinese dark tea, its extraction, and role in regulating inflammation and immune response. Food Research International, IF：8.0. 中科院一区

10. Chen Liu et al. (2025). Tibetan dark tea theabrownin alleviates LPS-induced inflammation by modulating the Nrf2/NF-κB signaling pathway and host microbial metabolites. Food Chemistry, IF：9.8. 中科院一区

11. Chen Liu* et al. (2025). Current and emerging issues in chemical food safety. Current Opinion in Food Science, IF：9.1. 中科院一区

12. Shengxiang Chen, […] , Chen Liu*. (2025). Multi-omics analysis reveals the sensory quality and fungal communities of Tibetan teas produced by wet- and dry-piling fermentation. Food Research International, IF：8.0. 中科院一区

13. Chen Liu et al. (2025). Cultivar-dependent variation in metabolomic profiles and sensory characteristics of Zhuyeqing green tea (Camellia sinensis). Food Bioscience, IF：5.9. 中科院二区TOP

14. Ting Zhang, […] , Chen Liu*. (2025). Multi-omics network analysis of flavour formation in golden-flowered Tibetan dark tea processed by “flowering” using raw materials with different fermentation degrees. Food Chemistry, IF：9.8. 中科院一区